منابع مشابه
Epigenetic regulation of cardiac myocyte differentiation†
Cardiac myocytes (CMs) proliferate robustly during fetal life but withdraw permanently from the cell cycle soon after birth and undergo terminal differentiation. This cell cycle exit is associated with the upregulation of a host of adult cardiac-specific genes. The vast majority of adult CMs (ACMs) do not reenter cell cycle even if subjected to mitogenic stimuli. The basis for this irreversible...
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Radiotherapy is a fundamental part of cancer treatment but its use is limited by the onset of late adverse effects in the normal tissue, especially radiation-induced fibrosis. Since the molecular causes for fibrosis are largely unknown, we analyse if epigenetic regulation might explain inter-individual differences in fibrosis risk. DNA methylation profiling of dermal fibroblasts obtained from b...
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A s deaths from acute myocardial infarction have declined dramatically over the past several decades, more and more patients survive with chronic myocardial ischemia. Hearts of most patients who survive acute myocardial infarction undergo remodeling. Hearts of most patients with sustained hyperten-sion, another common cardiovascular disease, also show some degree of remodeling. The heart consis...
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Understanding the regulation of cardiac fibrosis is critical for controlling adverse cardiac remodeling during heart failure. Previously we identified miR-378 as a cardiomyocytes-abundant miRNA downregulated in several experimental models of cardiac hypertrophy and in patients with heart failure. To understand the consequence of miR-378 down-regulation during cardiac remodeling, our current stu...
متن کاملpericystic fibrosis of a cardiac hydatid cyst
introduction cardiac hydatid cysts are rare and represent less than 2% of all hydatid cases. they can occur as part of a widespread systemic infection or an isolated event. case presentation here, we presented a case of cardiac hydatid cyst in interventricular septum. conclusions the case presented had some findings that suggested the specific diagnosis of hydatid cyst.
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ژورنال
عنوان ژورنال: Journal of Molecular and Cellular Cardiology
سال: 2016
ISSN: 0022-2828
DOI: 10.1016/j.yjmcc.2016.02.011